April 2018
With the recent advancement in DNA sequencing technologies, researches have been fortified to high-throughput, cost-efficient sequencing of many more genomes that was ever previously possible. The most prominent area of genomic sequencing and assembly, known as de-novo genome assembly, now-a-days makes it even possible for researchers to individually sequence the genome of their choosing organisms. […]
The human genome project showed that important genetic variations exist between individuals. The 1000 genomes project measures those genetic variations between individuals which help medical researchers to find disease causing gene. All the different genes found in the cells of human being are the human genome and it is the key to what makes us […]
Precise and efficient genome editing has triggered a revolution in making genetic manipulations possible essentially in all types of cells and organisms. There are many approaches like ZFNs and TALENs have been developed for genome editing. Among which, the most recent and broadly applicable one is CRISPR-Cas9 which is short for Clustered Regularly Interspaced Short […]
Protein-Protein docking is a kind of bioinformatics tool for studying protein-protein interaction. Protein-protein interaction plays important role in biological processes like signal transduction, cellular motion, gene regulation and transport, it is the way to find target for drug discovery. Generally, the protein structures which had high resolution and were determined by X-ray crystallography was considered […]
To understand the mechanism behind the function of a protein, its three-dimensional structure plays a central role. Various experimental methods to determine protein three-dimensional structure like X-ray crystallography, NMR, electron microscopy, etc. provide more authentic structures than the theoretical models but they are very time consuming and have their limits, as in case of membrane […]
Biopython is an open source application programming interface used by computational biologist and bioinformatician. Biopython is supported by Open Bioinformatics Foundation (OBF). It is the collection of Python tools, and it provides an online resource for modules, scripts, and web links for developers of Python based software for life science research. Python is an object […]