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NGS AND PCOS Genetics
NGS AND PCOS Genetics Study: To start with Polycystic ovary syndrome (PCOS), it is a highly complex endocrine disorder in reproductive females, which leads to reproductive, metabolic, as well as hormonal abnormalities and manifests a host of ovarian defects like impaired folliculogenesis, anovulation, and poor oocyte quality. Moreover Addressing the epigenetic anomalies that regulate [...]
MOLECULAR BIOLOGY: STUDY OF BIOMOLECULES
Generally, Molecular biology is the study of biomolecules like DNA, RNA and protein. The area interknits with the other areas of biology, Chemistry, Biochemistry and Genetics. However, Biochemistry is the study of chemical molecule and vital processes occurring in organisms. Biochemists mainly focus on role, functions and structure of biomolecule. Genetics is the study of [...]
Next-generation sequence data analysis: New and speedy approach for data analysis
NGS is a low-priced, speedy and high-throughput alternative to Sanger-method based DNA sequencing. It offers parallel-sequencing of millions of DNA fragments concurrently and allows an entire genome to be sequenced in a small time. NGS is basically a three-step process, namely: 1). Template preparation 2). Sequencing and imaging 3). Data analysis. All the platforms [...]
Data Management Challenges in Next Generation Sequencing
Since the beginning of the Human Genome Project, data management has been perceived as a key challenge for current molecular biology research. Before the finish of the nineties, advances had been set up that adequately bolstered most continuous activities, ordinarily based upon relational database management frameworks. Ongoing years have seen a sensational increment in the [...]
Perl/Bio-Perl: A Bioinformatics toolkit
Essentially, Perl is an interpreted programming language that is easily grasped by newcomers in the bioinformatics field. Additionally, it not only connects software applications together into sequence analysis pipelines, but it also converts file formats and extracts information from the output of analyzed programs. Moreover, Perl/Bio-Perl: A Bioinformatics toolkit is a collection of Perl modules [...]
Unriddle genomic codes using BioJava
Since the completion of the Human-genome project, deciphering the massive data produced becomes the primary focus of the scientist community. To analyse this data, bioinformaticians are required to develop such softwares and tools that can meet with the level of these complex data. The scalable, cross-platform, robust java framework leg-up the researchers to develop BioJava […]
