Bioinformatics

Unlocking the Secrets of Molecular Evolution with Modeltest 3.7 Modeltest is a software tool for selecting the best-fitting model of molecular evolution from a set of candidate models. This is done by comparing the likelihoods of different models, which are calculated using the maximum likelihood method. The model with the highest likelihood is considered the […]

DNA annotation or genome annotation identifies genes and all of the coding regions in a genome and determines what those genes do. Once a genome is sequenced, it needs to be annotated to make sense of it. Gene annotation involves the process of taking the raw DNA sequence produced by the genome-sequencing projects and adding […]

  NGS is a low-priced, speedy and high-throughput alternative to Sanger-method based DNA sequencing. It offers parallel-sequencing of millions of DNA fragments concurrently and allows an entire genome to be sequenced in a small time. NGS is basically a three-step process, namely: 1). Template preparation 2). Sequencing and imaging 3). Data analysis. All the platforms [...]

Since the beginning of the Human Genome Project, data management has been perceived as a key challenge for current molecular biology research. Before the finish of the nineties, advances had been set up that adequately bolstered most continuous activities, ordinarily based upon relational database management frameworks. Ongoing years have seen a sensational increment in the [...]

Since the completion of the Human-genome project, deciphering the massive data produced becomes the primary focus of the scientist community. To analyse this data, bioinformaticians are required to develop such softwares and tools that can meet with the level of these complex data. The scalable, cross-platform, robust java framework leg-up the researchers to develop BioJava […]

Answer: Bioinformatics Phenomenal amount of biological data of various types used to generate everyday, which when organised properly will help researchers to better utilise their scientific potential and knowledge. Bioinformatics is an interdisciplinary field of science to retrieve, analyze, store, share and manipulate biological data using computational tools and techniques. Bioinformatics finds its roots in [...]

Biotechnology In today’s world, the field of Biotechnology has made tremendous impact by helping to develop various new techniques and methods in science and research. Within the 20th and 21st century Biotechnology achieved a huge breakthrough in scientific research and development. The method of using biological systems, living organisms to obtain new products or modify […]

Genome-wide examinations concerning cooperative interactions among genomic functions, e.g. DNA replication, isolation, translation, repair and rearrangement, are fundamental for methodically explaining every single biological activity on the genome. To this end, chromatin immunoprecipitation pursued by sequencing (ChIP-seq) examination was produced to comprehend the collaboration and cooperations that happen in a wide assortment of living beings […]

According to the report, the Global Bioinformatics Services Market accounted for $1.3 billion in 2017 and is expected to reach $5.67 billion by 2026 growing at a CAGR of 17.8% during the forecast period. Factors such as rising public-private sector funding for bioinformatics services, increasing applications of bioinformatics in different industries and the lack of […]

Particularly to understand the interaction between both receptors as well as ligands, a pharmacophore is essential. Firstly, It is an important feature in the design of new drugs for the treatment of a specific disease. Moreover, Pharmacophore is defined as the essential geometric arrangement of atoms or functional groups necessary to produce a given biological [...]