Bioinformatics
NGS is a low-priced, speedy and high-throughput alternative to Sanger-method based DNA sequencing. It offers parallel-sequencing of millions of DNA fragments concurrently and allows an entire genome to be sequenced in a small time. NGS is basically a three-step process, namely: 1). Template preparation 2). Sequencing and imaging 3). Data analysis. All the platforms […]
Since the beginning of the Human Genome Project, data management has been perceived as a key challenge for current molecular biology research. Before the finish of the nineties, advances had been set up that adequately bolstered most continuous activities, ordinarily based upon relational database management frameworks. Ongoing years have seen a sensational increment in the […]
Since the completion of the Human-genome project, deciphering the massive data produced becomes the primary focus of the scientist community. To analyse this data, bioinformaticians are required to develop such softwares and tools that can meet with the level of these complex data. The scalable, cross-platform, robust java framework leg-up the researchers to develop BioJava […]
Answer: Bioinformatics Phenomenal amount of biological data of various types used to generate everyday, which when organised properly will help researchers to better utilise their scientific potential and knowledge. Bioinformatics is an interdisciplinary field of science to retrieve, analyze, store, share and manipulate biological data using computational tools and techniques. Bioinformatics finds its roots in […]
Biotechnology In today’s world, the field of Biotechnology has made tremendous impact by helping to develop various new techniques and methods in science and research. Within the 20th and 21st century Biotechnology achieved a huge breakthrough in scientific research and development. The method of using biological systems, living organisms to obtain new products or modify […]
Genome-wide examinations concerning cooperative interactions among genomic functions, e.g. DNA replication, isolation, translation, repair and rearrangement, are fundamental for methodically explaining every single biological activity on the genome. To this end, chromatin immunoprecipitation pursued by sequencing (ChIP-seq) examination was produced to comprehend the collaboration and cooperations that happen in a wide assortment of living beings […]
With the recent advancement in DNA sequencing technologies, researches have been fortified to high-throughput, cost-efficient sequencing of many more genomes that was ever previously possible. The most prominent area of genomic sequencing and assembly, known as de-novo genome assembly, now-a-days makes it even possible for researchers to individually sequence the genome of their choosing organisms. […]
The human genome project showed that important genetic variations exist between individuals. The 1000 genomes project measures those genetic variations between individuals which help medical researchers to find disease causing gene. All the different genes found in the cells of human being are the human genome and it is the key to what makes us […]
Precise and efficient genome editing has triggered a revolution in making genetic manipulations possible essentially in all types of cells and organisms. There are many approaches like ZFNs and TALENs have been developed for genome editing. Among which, the most recent and broadly applicable one is CRISPR-Cas9 which is short for Clustered Regularly Interspaced Short […]