Drug Discovery

Vaccines have been one of the most effective tools in the fight against infectious diseases, saving millions of lives each year. However, the process of developing and testing vaccines is long and costly, often taking several years and billions of dollars. In recent years, there has been a growing interest in using insilico techniques to […]

DNA annotation or genome annotation identifies genes and all of the coding regions in a genome and determines what those genes do. Once a genome is sequenced, it needs to be annotated to make sense of it. Gene annotation involves the process of taking the raw DNA sequence produced by the genome-sequencing projects and adding […]

DeepMind’s artificial intelligence system AlphaFold2, predicts the 3D structure of a protein based on its amino acid sequence. It looks to be a 50-year-old answer to the problem of protein folding. DeepMind’s AlphaFold1 was the first in the series, and it scored high in the 13th Critical Assessment of Protein Structure Prediction (Deepmind’s first effort […]

Particularly to understand the interaction between both receptors as well as ligands, a pharmacophore is essential. Firstly, It is an important feature in the design of new drugs for the treatment of a specific disease. Moreover, Pharmacophore is defined as the essential geometric arrangement of atoms or functional groups necessary to produce a given biological [...]