Molecular Modelling & Simulation
Protein interactions play important role in biological field and hence their characterization to reveal their structure and functionhas become important.In absence of experimentally determined structures, proteins can be modeled using computational methods. There is an increase in number of known protein sequences since the computational tools for modelling have been built. Modeller is one of […]
Protein-Protein docking is a kind of bioinformatics tool for studying protein-protein interaction. Protein-protein interaction plays important role in biological processes like signal transduction, cellular motion, gene regulation and transport, it is the way to find target for drug discovery. Generally, the protein structures which had high resolution and were determined by X-ray crystallography was considered […]
To understand the mechanism behind the function of a protein, its three-dimensional structure plays a central role. Various experimental methods to determine protein three-dimensional structure like X-ray crystallography, NMR, electron microscopy, etc. provide more authentic structures than the theoretical models but they are very time consuming and have their limits, as in case of membrane […]
