Computer Aided Drug Discovery

Vaccines have been one of the most effective tools in the fight against infectious diseases, saving millions of lives each year. However, the process of developing and testing vaccines is long and costly, often taking several years and billions of dollars. In recent years, there has been a growing interest in using insilico techniques to […]

Primer Designing By Primer Blast Primers serve a crucial function in identifying the target area of the complex genome [1]. Primers or oligonucleotides are short sequences of DNA or RNA that are complementary to a particular DNA sequence, allowing replication to occur during a PCR cycle. Primers may also be used in various techniques, including […]

DeepMind’s artificial intelligence system AlphaFold2, predicts the 3D structure of a protein based on its amino acid sequence. It looks to be a 50-year-old answer to the problem of protein folding. DeepMind’s AlphaFold1 was the first in the series, and it scored high in the 13th Critical Assessment of Protein Structure Prediction (Deepmind’s first effort […]

The production of large amount of compounds is the characterization of modern drug discovery. This huge libraries of compounds need to be examine in short periods of time. So, Computer aided drug design has came out as a method for developing candidate drug for treatment of many disease types. The discovery of drug and developing […]

Computer aided drug designing aims for medical chemistry that designs methods in modern medicinal chemistry such that its’ cost with respect to depletes and it uses one fastest growing approach of pharmacophore modeling. Pharmacophore modeling is a technique where a large number of molecules can be filtered and segregate molecules on few or more identical […]

Particularly to understand the interaction between both receptors as well as ligands, a pharmacophore is essential. Firstly, It is an important feature in the design of new drugs for the treatment of a specific disease. Moreover, Pharmacophore is defined as the essential geometric arrangement of atoms or functional groups necessary to produce a given biological [...]