Courses
A number of human genetic disorders cause chromosomal breakage, which is characterized by genome instability. Genome instability is associated with immune deficiency, a predisposition to develop cancer, and premature aging . Mutations in the BLM or RECQL3 gene located on chromosome 15 which encodes a DNA helicase in the RecQ family cause Bloom syndrome. The RecQ family is […]
Application of NGS in PCOS Study: Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder in reproductive females, which leads to reproductive, metabolic and hormonal abnormalities and manifest a host of ovarian defects like impaired folliculogenesis, anovulation, and poor oocyte quality. Addressing the epigenetic anomalies that regulate adverse events is of foremost importance in […]
Molecular biology is the study of biomolecules like DNA, RNA and protein. The area interknits with the other areas of biology, Chemistry, Biochemistry and Genetics. However, Biochemistry is the study of chemical molecule and vital processes occurring in organisms. Biochemists mainly focus on role, functions and structure of biomolecule. Genetics is the study of effect […]
 NGS is a low-priced, speedy and high-throughput alternative to Sanger-method based DNA sequencing. It offers parallel-sequencing of millions of DNA fragments concurrently and allows an entire genome to be sequenced in a small time. NGS is basically a three-step process, namely: 1). Template preparation 2). Sequencing and imaging 3). Data analysis. All the platforms […]
Since the beginning of the Human Genome Project, data management has been perceived as a key challenge for current molecular biology research. Before the finish of the nineties, advances had been set up that adequately bolstered most continuous activities, ordinarily based upon relational database management frameworks. Ongoing years have seen a sensational increment in the […]
Perl is an interpreted programming language and this language easily gasped by newcomers of bioinformatics field. It connects the software applications together into sequence analysis pipelines, converts the file format and extracts the information from output of analyzed programs. Bioperl is a collection of Perl modules and provides easy to use, stable and consistent interface […]
Since the completion of the Human-genome project, deciphering the massive data produced becomes the primary focus of the scientist community. To analyse this data, bioinformaticians are required to develop such softwares and tools that can meet with the level of these complex data. The scalable, cross-platform, robust java framework leg-up the researchers to develop BioJava […]
Answer: Bioinformatics Phenomenal amount of biological data of various types used to generate everyday, which when organised properly will help researchers to better utilise their scientific potential and knowledge. Bioinformatics is an interdisciplinary field of science to retrieve, analyze, store, share and manipulate biological data using computational tools and techniques. Bioinformatics finds its roots in […]
Biotechnology In today’s world, the field of Biotechnology has made tremendous impact by helping to develop various new techniques and methods in science and research. Within the 20th and 21st century Biotechnology achieved a huge breakthrough in scientific research and development. The method of using biological systems, living organisms to obtain new products or modify […]
Chemoinformatics is an application of computational molecular science to solve chemical problem by manipulating chemical structural information of compounds. It is a distinct discipline which combines Physics, Chemistry, Biology, Biochemistry, mathematics, Statistics and Information technology. The goal of chemoinformatics is to gather information by analyzing, stimulating and modelling of chemical structure either in 2D or […]