Bioinformatics

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Why de-novo genome assembly?
20
Apr
1

With the recent advancement in DNA sequencing technologies, researches have been fortified to high-throughput, cost-efficient sequencing of many more genomes that was ever previously possible. The most prominent area of genomic sequencing and assembly, known as de-novo genome assembly, now-a-days makes it even possible for researchers to individually sequence the genome of their choosing organisms. […]

Posted in: Bioinformatics , Next Generation Sequencing ,
THE 1000 GENOMES PROJECT: STUDY OF GENETIC VARIATION
16
Apr
1

The human genome project showed that important genetic variations exist between individuals. The 1000 genomes project measures those genetic variations between individuals which help medical researchers to find disease causing gene. All the different genes found in the cells of human being are the human genome and it is the key to what makes us […]

Posted in: Bioinformatics ,
CRISPR-Cas9 technique in the lab
13
Apr
4

Precise and efficient genome editing has triggered a revolution in making genetic manipulations possible essentially in all types of cells and organisms. There are many approaches like ZFNs and TALENs have been developed for genome editing. Among which, the most recent and broadly applicable one is CRISPR-Cas9 which is short for Clustered Regularly Interspaced Short […]

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